Pharmacology · single question
Which pharmacological intervention is MOST effective for smoking cessation?
Show answer and explanation
Correct answer: D. Varenicline (Chantix)
VARENICLINE (Chantix) = most effective single pharmacologic agent for smoking cessation. Partial agonist of nicotinic acetylcholine receptors — reduces cravings and withdrawal while blunting nicotine reward. Combination NRT also highly effective. Bupropion = effective but less so.