Endodontics · patient case question

Which organisms predominate in a primary endodontic infection?

Patient case: The Tooth That Jumped Mid-Treatment

Patient: 39-year-old male

Chief Complaint: Referred for root canal treatment of tooth #14. He reports no symptoms at all.

Background: Large restoration placed years ago. Routine radiograph revealed an apical lesion.

Medications: None

Vital Signs: BP 122/76 mmHg · HR 72 bpm · RR 16 · T 98.4°F

Findings: Tooth #14 is asymptomatic and does not respond to cold, with a well-defined apical radiolucency. Under local anaesthesia the canals are being negotiated when the patient suddenly jumps in pain as a file advances. Later in the appointment, after instrumentation, one canal bleeds persistently on irrigation.

  1. Facultative aerobes
  2. Microaerophiles exclusively
  3. Obligate anaerobes
  4. Obligate aerobes
Show answer and explanation

Correct answer: C. Obligate anaerobes

  • A. Facultative organisms are present but are a minority in PRIMARY infections. They become important in SECONDARY and PERSISTENT infections — Enterococcus faecalis is the classic facultative organism of failed root canal treatment, surviving because it tolerates high pH and nutrient deprivation.
  • B. Microaerophiles are a minor component, not the predominant group.
  • C. CORRECT. Primary endodontic infections are POLYMICROBIAL and dominated by OBLIGATE ANAEROBES — typically 90% or more of the flora. The necrotic canal has no circulation, no oxygen and a low redox potential, which selects strongly for anaerobic growth. Common isolates include Porphyromonas, Prevotella, Fusobacterium, Peptostreptococcus and Dialister.
  • D. Obligate aerobes cannot survive in the anoxic environment of a necrotic root canal.

Note: Clinical link: this is why metronidazole (active only against anaerobes) is a rational adjunct in endodontic infection, and why the shift to E. faecalis in retreatment cases changes the disinfection strategy.

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