Which of the following statements is correct regarding type 2 diabetes mellitus?

Most obese individuals eventually develop type 2 diabetes
It is caused by autoimmune destruction of pancreatic ╬▓ cells
It is characterized by insulin resistance and relative insulin deficiency
It requires lifelong exogenous insulin from diagnosis

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Correct answer: C. It is characterized by insulin resistance and relative insulin deficiency

Type 2 DM is primarily a disease of insulin resistance in peripheral tissues (muscle, liver, adipose) combined with a progressive decline in ╬▓-cell function. Type 1 DM (not type 2) is due to autoimmune ╬▓-cell destruction. Not all obese patients develop diabetes, and insulin is often unnecessary early in type 2 disease.

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Which of the following statements is correct regarding type 2 diabetes mellitus?

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