Anatomy & Histology · patient case question
Which of the following is associated with bone resorption?
Patient case: Bone biology and drug mechanisms
Scenario: One histology item followed by a run of mechanism-of-action questions.
Show answer and explanation
Correct answer: D. Howship lacunae
- A. The endosteum is the membrane lining the medullary cavity. It contains osteoprogenitor cells and is a site of both formation and resorption, but it is not the resorption feature itself.
- B. Canaliculi are the tiny channels housing osteocyte processes; they permit communication and mechanosensation, not resorption.
- C. Haversian canals carry the neurovascular bundle at the centre of each osteon — a structural feature of compact bone.
- D. Correct. Howship lacunae are the scalloped depressions on a bone surface excavated by actively resorbing osteoclasts, which sit within them behind a ruffled border and sealing zone.
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