Pathology · single question

Which of the following is an EXCEPTION in ectodermal dysplasia?

  1. Dry eyes
  2. Y-linked inheritance
  3. Heat intolerance
  4. Sparse hair and missing teeth
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Correct answer: B. Y-linked inheritance

Ectodermal dysplasia is X-linked (hypohidrotic form, XLHED), NOT Y-linked. Classic findings: anodontia/hypodontia, sparse hair (hypotrichosis), inability to sweat (anhidrosis), dry eyes, and heat intolerance. Y-linked inheritance is the exception — the condition is X-linked recessive, primarily affecting males, with females being carriers.

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