Pharmacology · single question
Which of the following is a COMPLETE (absolute) contraindication for methylprednisolone?
Show answer and explanation
Correct answer: C. Active systemic fungal infection
C) Active systemic fungal infection — CORRECT.
Systemic corticosteroids (like methylprednisolone) are absolutely contraindicated in patients with active systemic fungal infections because they suppress the immune response needed to control the infection, leading to potentially fatal dissemination.
A) Hypertension: A relative contraindication (steroids can raise BP) but not absolute. Requires monitoring.
B) Diabetes: A relative contraindication (steroids cause hyperglycemia) but patients can still receive steroids with careful blood glucose management.
D) Mild asthma: Corticosteroids are actually used to TREAT asthma — not contraindicated.
Systemic corticosteroids (like methylprednisolone) are absolutely contraindicated in patients with active systemic fungal infections because they suppress the immune response needed to control the infection, leading to potentially fatal dissemination.
A) Hypertension: A relative contraindication (steroids can raise BP) but not absolute. Requires monitoring.
B) Diabetes: A relative contraindication (steroids cause hyperglycemia) but patients can still receive steroids with careful blood glucose management.
D) Mild asthma: Corticosteroids are actually used to TREAT asthma — not contraindicated.