Anesthesia · single question

Which local anesthetic should be AVOIDED in a pregnant patient?

  1. Mepivacaine (plain, without vasoconstric­tor)
  2. Lidocaine 2% with epinephrine
  3. Lidocaine without epinephrine
  4. Articaine 4% with epinephrine
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Correct answer: A. Mepivacaine (plain, without vasoconstric­tor)

  • A. ✅ Correct. MEPIVACAINE (plain, without vasoconstrictor) has a prolonged fetal half-life and is associated with fetal bradycardia. It is the anesthetic most contraindicated in pregnancy from the listed options.
  • B. ❌ Lidocaine 2% with epinephrine is FDA Category B and is the PREFERRED anesthetic in pregnancy (in appropriate doses).
  • C. ❌ Lidocaine without epinephrine is also Category B and safe.
  • D. ❌ Articaine 4% with epinephrine is widely used and considered acceptable in pregnancy (Category C but in clinical practice deemed safe at appropriate doses).

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