Anesthesia · single question

Which local anesthetic is SAFEST for a pregnant patient?

  1. Mepivacaine
  2. Articaine
  3. Lidocaine
  4. Tetracaine
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Correct answer: C. Lidocaine

✓ C) Lidocaine is correct.
Lidocaine with epinephrine is the safest, most well-studied local anesthetic for use during pregnancy (FDA Category B). It has the longest safety record and extensive clinical evidence of safe use in pregnant patients. Mepivacaine and bupivacaine have higher protein binding and longer half-lives. Articaine has limited pregnancy safety data. Tetracaine is a topical/spinal anesthetic not used for routine dental infiltration. Epinephrine is safe in pregnancy at dental concentrations (1:100,000) as it minimizes systemic absorption and maintains local effect.

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