Biostatistics & Research · single question

Which is the FUNDAMENTAL requirement that defines a randomized controlled trial?

  1. Random allocation of participants to groups
  2. Single blinding
  3. Crossover design
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Correct answer: A. Random allocation of participants to groups

  • A. Correct. RANDOM allocation to comparison groups is the defining feature, minimizing selection bias and balancing confounders.
  • B. Incorrect. Blinding strengthens an RCT but is not what defines it (some RCTs are open-label).
  • C. Incorrect. Crossover is one optional RCT variant, not a defining requirement.

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