Physiology & Biochemistry · single question

Which immunoglobulin is the predominant one present in saliva?

  1. IgA
  2. IgG
  3. IgE
  4. IgM
Show answer and explanation

Correct answer: A. IgA

Secretory IgA is the predominant immunoglobulin in saliva and other mucosal secretions, providing a first-line 'immune exclusion' defense against pathogens at mucosal surfaces — distinct from IgG (the main immunoglobulin in blood/systemic circulation), IgE (allergic/parasitic responses), and IgM (early systemic immune response).

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