Which HPV type is most strongly associated with oropharyngeal cancer?

HPV-16 is the high-risk genotype most strongly and consistently linked to HPV-associated oropharyngeal squamous cell carcinoma. HPV-18 is more associated with cervical cancer; HPV-6 and HPV-11 are low-risk types associated with benign lesions like genital warts/oral papillomas, not malignancy.