Which disease occurs most commonly in the submandibular salivary gland?

SIALOLITHIASIS (salivary stones / calculi) occurs MOST COMMONLY in the SUBMANDIBULAR GLAND (~80-90% of all salivary stones). This is because: (1) Wharton's duct is long and travels upward (against gravity), (2) submandibular saliva is more mucous, alkaline, and calcium-rich → predisposed to calcification. MUCOCELES occur most commonly in the LOWER LIP (minor salivary glands). SJÖGREN'S affects all major glands. Necrotizing sialometaplasia is found in palate. C is correct.