Pathology · single question
Which condition is characterized by the presence of Reed-Sternberg cells?
Show answer and explanation
Correct answer: D. Hodgkin's lymphoma
- A. Non-Hodgkin's lymphoma involves malignant B or T cells but does NOT feature Reed-Sternberg cells — this is the key distinguishing feature.
- B. Multiple myeloma is a malignancy of plasma cells, not characterized by Reed-Sternberg cells.
- C. Leukemia involves malignant white blood cell precursors in the bone marrow; Reed-Sternberg cells are not a feature.
- D. Correct. Reed-Sternberg cells are large, binucleated or multinucleated malignant B cells ('owl-eye' appearance) that are pathognomonic for Hodgkin's lymphoma. Their presence on biopsy is required for diagnosis.