Pathology · single question
Which clinical feature is characteristic of Addison disease (primary adrenal insufficiency)?
Show answer and explanation
Correct answer: A. Diffuse mucocutaneous hyperpigmentation
In Addison disease, low cortisol increases ACTH/MSH, producing diffuse bronze hyperpigmentation of skin and oral mucosa, along with fatigue, hypotension, and salt craving.Other options: Hypopigmentation, gingival overgrowth, and macroglossia are not features of Addison disease.Key exam takeaway: Addison disease = hyperpigmentation (skin and oral mucosa) from elevated ACTH/MSH.