Anatomy & Histology · single question

Which cell type is responsible for tooth root resorption?

  1. Odontoclasts (clastic cells)
  2. Osteoblasts
  3. Odontoblasts
  4. Cementoblasts
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Correct answer: A. Odontoclasts (clastic cells)

Odontoclasts (also called cementoclasts or dentinoclasts) are multinucleated giant cells that resorb the hard tissues of the tooth root (cementum and dentin). They are functionally analogous to osteoclasts (which resorb bone) and share similar morphology and enzyme expression (tartrate-resistant acid phosphatase, cathepsin K). Root resorption can be physiological (primary tooth resorption before eruption of permanent teeth) or pathological (from orthodontic forces, periapical infection, or trauma). Note: Q98 below distinguishes that osteoclasts resorb bone (alveolar bone), while odontoclasts resorb cementum and dentin.

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