Pharmacology · single question

What is the therapeutic/normal INR range for a patient on warfarin therapy?

  1. 3.5–4.5
  2. 1.0–2.0
  3. 1.5–2.0
  4. 2.0–3.0
Show answer and explanation

Correct answer: D. 2.0–3.0

  • A. 3.5–4.5 is SUPRATHERAPEUTIC — dangerous bleeding risk. Only used for specific high-risk mechanical valve cases.
  • B. 1.0–2.0 is sub-therapeutic — 1.0 is normal (no anticoagulation).
  • C. 1.5–2.0 is below the therapeutic range — insufficient anticoagulation for most indications.
  • D. The NORMAL THERAPEUTIC INR range for most patients on warfarin (e.g., for DVT/PE prophylaxis, atrial fibrillation, mechanical heart valves in some cases) is 2.0–3.0. For patients with mechanical prosthetic heart valves, a higher range (2.5–3.5) may be targeted.

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