Oral Surgery · single question

What is the recommended management for oral mucositis in patients undergoing cancer therapy?

  1. Replace chlorhexidine (CHX) with povidone-iodine (iodopovidone) rinse
  2. Increase chlorhexidine concentration
  3. Use normal saline or sodium bicarbonate rinses and good oral hygiene
  4. Apply topical tetracycline ointment
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Correct answer: C. Use normal saline or sodium bicarbonate rinses and good oral hygiene

The standard management of oral mucositis involves gentle oral hygiene, bland rinses (saline or sodium bicarbonate), and palliation. Chlorhexidine is NOT recommended for mucositis prevention in most current guidelines (MASCC/ISOO) as it has not been shown to reduce mucositis severity. Switching from CHX to povidone-iodine is NOT evidence-based for this indication. Palifermin (keratinocyte growth factor) and low-level laser therapy (LLLT) are evidence-based interventions in specific settings.

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