Pathology · single question

What is the pathognomonic oral manifestation of measles (rubeola)?

  1. Positive Nikolsky sign
  2. Koplik spots
  3. White pseudomembrane
  4. Vesicular eruption on the palate
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Correct answer: B. Koplik spots

  • A. Nikolsky sign is seen in pemphigus vulgaris and toxic epidermal necrolysis — not measles.
  • B. Koplik spots are pathognomonic for measles. They appear as small white/bluish-white spots on a red base on the buccal mucosa (opposite lower molars), emerging 1–2 days BEFORE the skin rash.
  • C. White pseudomembrane is characteristic of pseudomembranous candidiasis or diphtheria.
  • D. Vesicular eruption on the palate occurs in herpangina (Coxsackievirus), not measles.

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