Pharmacology · single question
What is the most appropriate reversal agent for a patient who presents confused and uncoordinated after taking oral diazepam (Valium) for dental anxiety?
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Correct answer: A. Flumazenil (Romazicon)
- A. Correct. Flumazenil is a competitive benzodiazepine antagonist that reverses the sedative, amnestic, and respiratory depressant effects of benzodiazepines (including diazepam). It is the specific reversal agent for benzodiazepine overdose.
- B. Acetylcysteine reverses acetaminophen (Tylenol) hepatotoxicity — not benzodiazepine overdose.
- C. Naloxone (Narcan) is an opioid (mu receptor) antagonist — it reverses opioid toxicity (e.g., morphine, fentanyl), not benzodiazepine effects.
- D. Atropine is a muscarinic antagonist used for bradycardia and organophosphate poisoning — not benzodiazepine reversal.