Start practicing

Pharmacology · single question

What is the mechanism of action of candesartan?

  1. Directly inhibits renin
  2. Prevents conversion of angiotensin I to angiotensin II
  3. Effectively blocks angiotensin II (ARB)
  4. Inhibits beta-adrenergic receptors
Show answer and explanation

Correct answer: C. Effectively blocks angiotensin II (ARB)

  • A. Direct renin inhibition is the mechanism of aliskiren — not candesartan.
  • B. PREVENTING conversion of Ang I → Ang II is the mechanism of ACE INHIBITORS (lisinopril, enalapril) — NOT ARBs like candesartan.
  • C. Candesartan is an ANGIOTENSIN RECEPTOR BLOCKER (ARB) — it BLOCKS the AT1 receptor for angiotensin II, preventing vasoconstriction and aldosterone release. Unlike ACE inhibitors (which prevent Ang II formation), ARBs block its ACTION at the receptor. Candesartan does NOT cause the dry cough associated with ACE inhibitors (no bradykinin accumulation).
  • D. Beta-blocker mechanism (metoprolol, atenolol) — not candesartan.

Practice Pharmacology questions Pharmacology study notes

More Pharmacology practice questions