Pathology · patient case question

What is the essential next step?

Patient case: Woman with a soap-bubble radiolucency in the maxilla

Patient: Female, 65 years old

Chief complaint: Referred following an abnormal radiographic finding.

Background: Treated for breast cancer 2 years ago.

Current findings: Bone loss across all maxillary left quadrant teeth. A radiolucent lesion with a soap-bubble appearance lies between teeth #2 and #3.

  1. Incisional biopsy for histopathological diagnosis
  2. Radiographic review in six months
  3. Enucleation and curettage
  4. Immediate resection with wide margins
Show answer and explanation

Correct answer: A. Incisional biopsy for histopathological diagnosis

  • A. CORRECT. No definitive treatment may be planned from a radiographic impression alone. An INCISIONAL BIOPSY establishes the histological diagnosis and distinguishes between the possibilities — which here range from a benign odontogenic tumour to metastatic carcinoma, with entirely different management pathways.
  • B. Observation of an undiagnosed destructive lesion in a patient with a cancer history is unacceptable.
  • C. Enucleation presupposes a diagnosis that has not yet been made, and would be inadequate for either ameloblastoma or metastasis.
  • D. Resection without a tissue diagnosis is indefensible.

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