Medical Emergencies · single question

The same patient with a prosthetic mitral valve and childhood rheumatic fever. What antibiotic prophylaxis is indicated before invasive dental procedures?

  1. Amoxicillin 2 g orally 1 hour before the procedure
  2. No prophylaxis needed
  3. Clindamycin 300 mg orally 1 hour before the procedure
  4. Antibiotics only if signs of infection are present
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Correct answer: A. Amoxicillin 2 g orally 1 hour before the procedure

  • A. Correct. A prosthetic heart valve is a high-risk cardiac condition requiring infective-endocarditis prophylaxis: amoxicillin 2 g orally one hour before procedures that manipulate gingiva/periapical tissue.
  • B. Prophylaxis IS needed — prosthetic valves are a primary indication.
  • C. Clindamycin is the alternative for penicillin allergy, but the standard dose is 600 mg (not 300 mg), so this option is incorrect for a non-allergic patient.
  • D. Waiting for signs of infection defeats the purpose of pre-procedural prophylaxis.

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