Micro & Immunology · single question

The primary function of secretory IgA in the oral cavity is:

  1. Complement activation via classical pathway
  2. Mast cell degranulation
  3. Antibacterial and antiviral defense at mucosal surfaces
  4. Opsonization for phagocytosis
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Correct answer: C. Antibacterial and antiviral defense at mucosal surfaces

sIgA provides immune exclusion — neutralizes bacteria/viruses and prevents adherence to epithelium. Does NOT efficiently activate complement (IgG/IgM do). Does not opsonize well (IgG does). IgE triggers mast cell degranulation.

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