Pathology · single question
The histopathology of cherubism most closely resembles which of the following?
Show answer and explanation
Correct answer: C. Brown tumor (of hyperparathyroidism)
Cherubism is histologically a giant cell lesion (multinucleated giant cells in a fibrovascular stroma) that is essentially indistinguishable under the microscope from central giant cell granuloma and the brown tumor of hyperparathyroidism — diagnosis in all three requires correlating the histology with clinical/radiographic/laboratory findings, since the microscopic picture alone looks the same.