Oral Surgery · single question

Squamous cell carcinoma (SCC) of the mandible or tongue most commonly metastasizes to:

  1. Brain
  2. Lungs (hematogenous spread) and cervical lymph nodes (lymphatic spread)
  3. Liver
  4. Bone
Show answer and explanation

Correct answer: B. Lungs (hematogenous spread) and cervical lymph nodes (lymphatic spread)

  • A. Brain metastasis is an uncommon pattern for oral SCC.
  • B. Correct. Oral SCC metastasizes both lymphatically (to cervical lymph nodes — the first sign of spread) and hematogenously (to distant sites, most commonly the LUNGS). The lungs are the most common site of distant metastasis for head and neck SCC.
  • C. Liver metastasis occurs with oral SCC but is less common than lung metastasis.
  • D. Bone metastasis can occur but is less common than lung or cervical node spread.

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