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Anesthesia · single question

Primary cause of tissue necrosis following vasoconstrictor injection?

  1. Infection introduced by needle
  2. Allergic reaction to epinephrine
  3. Tissue ischemia from vasoconstriction
  4. Direct toxicity of local anesthetic
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Correct answer: C. Tissue ischemia from vasoconstriction

Vasoconstrictors (epinephrine) cause prolonged local vasoconstriction → TISSUE ISCHEMIA → necrosis in areas with limited collateral circulation (palate, digital ring blocks near end-arteries).

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