Anesthesia · single question

Phentolamine mesylate is used in dentistry for which purpose?

  1. Reversal of soft-tissue local anesthesia (vasodilator that speeds anesthetic clearance)
  2. Prolonging anesthesia
  3. Reversing benzodiazepine sedation
  4. Reversing opioid overdose
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Correct answer: A. Reversal of soft-tissue local anesthesia (vasodilator that speeds anesthetic clearance)

Phentolamine is an alpha-adrenergic blocker that vasodilates and accelerates removal of local anesthetic with vasoconstrictor, hastening recovery of normal soft-tissue sensation.Other options: It does not prolong anesthesia; flumazenil reverses benzodiazepines and naloxone reverses opioids.Key exam takeaway: Phentolamine reverses soft-tissue local anesthesia (alpha-blocker vasodilation).

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