Pharmacology · single question

Patient with Hep B and 2-year-old history of substance abuse (now sober). Most appropriate pain management?

  1. Oxycodone + acetaminophen
  2. Tramadol 50mg
  3. Ibuprofen + acetaminophen
  4. Hydrocodone + acetaminophen
Show answer and explanation

Correct answer: C. Ibuprofen + acetaminophen

Two concerns: (1) Hep B = avoid hepatotoxic drugs; (2) Substance abuse history = avoid opioids (relapse risk). IBUPROFEN + ACETAMINOPHEN (standard doses) provides adequate analgesia with minimal hepatotoxic and addiction risk. Best option.

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