Oral Surgery · single question

Osteoinduction by allograft involves all of the following growth factors EXCEPT:

  1. BMP (bone morphogenetic protein)
  2. TGF-β
  3. IL-1β
  4. PDGF
Show answer and explanation

Correct answer: C. IL-1β

Osteoinductive growth factors include BMP, TGF-β, PDGF, IGF; IL-1β is an inflammatory cytokine.
  • A. BMPs are the principal osteoinductive factors.
  • B. TGF-β contributes to osteoinduction.
  • C. Correct — the exception. IL-1β is a pro-inflammatory cytokine, not an osteoinductive growth factor.
  • D. PDGF participates in bone regeneration signaling.

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