Pathology · patient case question

On the same examination, a diffuse greyish-white opacity of the buccal mucosa DISAPPEARS when the cheek is stretched. What is it?

Patient case: Rampant interproximal caries in a smoker who chews mints

Patient: Male, 34 years old

Chief Complaint: “I keep getting cavities between my teeth even though I brush.”

Background: Smokes half a pack a day. Reports brushing twice daily with a fluoride toothpaste. Uses sugar-containing breath mints continuously through the working day to mask the smell of smoke.

Current Findings: Carious lesions on virtually every interproximal surface. Diffuse brown-black pigmentation distributed symmetrically along the attached gingiva of both arches, unchanged for as long as he can remember.

  1. Leukoplakia
  2. Leukoedema
  3. White sponge nevus
  4. Lichen planus
Show answer and explanation

Correct answer: B. Leukoedema

  • A. Leukoplakia is a white patch that CANNOT be rubbed off or made to disappear by stretching, and is a diagnosis of exclusion with malignant potential requiring biopsy.
  • B. CORRECT. Leukoedema is intracellular oedema of the spinous layer producing a diffuse, filmy, greyish-white appearance of the buccal mucosa. The defining diagnostic manoeuvre is that STRETCHING the mucosa makes it disappear. It is a benign variation of normal, more common in darker-skinned individuals and in smokers, and needs no treatment.
  • C. White sponge nevus is an autosomal dominant condition producing thick, folded, spongy white plaques from childhood; it persists on stretching.
  • D. Lichen planus presents with reticular Wickham's striae, bilateral and persistent, and does not vanish on stretching.

Practice Pathology questions Pathology study notes

More Pathology practice questions