Pathology · single question

Nodule on buccal mucosa that blanches with pressure. Diagnosis:

  1. Varix (venous varicosity)
  2. Amalgam tattoo
  3. Melanoma
  4. Fibroma
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Correct answer: A. Varix (venous varicosity)

  • A. Correct. A varix is a dilated, blood-filled venous lesion that characteristically blanches (empties of blood) with applied pressure — the key diagnostic clinical sign.
  • B. An amalgam tattoo does NOT blanch with pressure since it represents embedded metal particles in the tissue, not a vascular lesion.
  • C. Melanoma also does not blanch with pressure (pigment is melanin, not blood) and presents with more concerning features (irregular borders, rapid growth).
  • D. A fibroma is a firm fibrous nodule that does not blanch with pressure since it's not a vascular lesion.

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