Pathology · single question

MRONJ (Medication-Related Osteonecrosis of the Jaw) management is primarily:

  1. Radiation therapy to the jaw
  2. Aggressive surgical debridement immediately
  3. Conservative management (chlorhexidine rinse, antibiotics, avoid surgery initially)
  4. Hyperbaric oxygen only
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Correct answer: C. Conservative management (chlorhexidine rinse, antibiotics, avoid surgery initially)

  • A. Radiation therapy is not indicated for MRONJ.
  • B. Immediate aggressive surgery can worsen MRONJ by exposing more bone — this is generally avoided.
  • C. Correct. MRONJ management is primarily CONSERVATIVE: chlorhexidine mouth rinses for antisepsis, systemic antibiotics for infection, pain management, avoidance of surgical intervention when possible. If surgery is required, refer to maxillofacial surgery. The goal is to control symptoms and prevent progression while avoiding further bone exposure.
  • D. Hyperbaric oxygen is used adjunctively in some cases but is not first-line conservative management.

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