Biostatistics & Research · single question

In the PICO framework for evidence-based questions, the 'C' stands for:

  1. Comparison (comparator/intervention being compared)
  2. Contralateral
  3. Confounder
  4. Control group only
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Correct answer: A. Comparison (comparator/intervention being compared)

  • A. Correct. PICO = Population, Intervention, Comparison, Outcome. 'C' is the comparison (the alternative intervention or control being compared).
  • B. 'Contralateral' is not a PICO element.
  • C. 'Confounder' is a study-design concept, not the 'C' in PICO.
  • D. While a control group can be the comparator, the PICO term itself is 'Comparison'.

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