Pharmacology · single question
In a patient with G6PD deficiency, which risk is associated with certain local anesthetics (e.g., prilocaine/benzocaine)?
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Correct answer: C. Methemoglobinemia (and hemolytic anemia)
- A. Incorrect – caused by serotonergic drug combinations, not LA in G6PD.
- B. Incorrect – that is triggered by volatile anesthetics/succinylcholine via RYR1 mutations, unrelated to G6PD.
- C. Correct – G6PD-deficient red cells are vulnerable to oxidative stress; prilocaine/benzocaine can induce methemoglobinemia and hemolysis.
- D. Incorrect – not the characteristic G6PD complication.