Anatomy & Histology · single question

If a bolus injection is given into the tongue, where does the drug PRIMARILY drain?

  1. Facial vein → external jugular vein
  2. Lingual vein → internal jugular vein
  3. Submandibular lymph nodes only
  4. Directly into systemic circulation via arterial uptake
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Correct answer: B. Lingual vein → internal jugular vein

The tongue drains venously via the lingual vein → internal jugular vein (and then to the subclavian vein and superior vena cava). A bolus injection into the tongue would primarily drain into the lingual vein, which empties into the internal jugular vein. This is why intravenous drug injection into the tongue (or sublingual IV access in emergencies) delivers drugs into the systemic venous circulation rapidly via the internal jugular.

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