Oral Surgery · single question
Ibandronate (a bisphosphonate) is associated with what significant oral risk?
Show answer and explanation
Correct answer: A. Osteonecrosis of the jaw (MRONJ)
✓ A) Osteonecrosis of the jaw (MRONJ) is correct.
Ibandronate is an oral bisphosphonate used for osteoporosis. All bisphosphonates carry risk of Medication-Related Osteonecrosis of the Jaw (MRONJ) — exposed necrotic bone lasting >8 weeks, not healing despite treatment. Risk factors: IV > oral bisphosphonates; longer duration; invasive dental procedures (extractions, implants). The 2014 AAOMS position paper gives staging criteria. For oral bisphosphonate patients: calculate cumulative dose, drug holiday (>4 years use), and avoid elective invasive procedures when possible.
Ibandronate is an oral bisphosphonate used for osteoporosis. All bisphosphonates carry risk of Medication-Related Osteonecrosis of the Jaw (MRONJ) — exposed necrotic bone lasting >8 weeks, not healing despite treatment. Risk factors: IV > oral bisphosphonates; longer duration; invasive dental procedures (extractions, implants). The 2014 AAOMS position paper gives staging criteria. For oral bisphosphonate patients: calculate cumulative dose, drug holiday (>4 years use), and avoid elective invasive procedures when possible.