Medical Emergencies · single question

Hypothyroidism is best characterized clinically by which of the following symptoms?

  1. Hypertension, flushing, headache
  2. Lethargy, weight gain, cold intolerance
  3. Palpitations, weight loss, exophthalmos
  4. Polyuria, polydipsia, fatigue
Show answer and explanation

Correct answer: B. Lethargy, weight gain, cold intolerance

  • A. Hypertension, flushing, and headache suggest a pheochromocytoma — not hypothyroidism.
  • B. Correct. Hypothyroidism is characterized by a SLOWING of metabolism: lethargy/fatigue, weight gain, cold intolerance, constipation, depression, bradycardia, dry skin, and hair loss. Myxedema is the term for severe hypothyroidism.
  • C. Palpitations, weight loss, and exophthalmos are signs of HYPERTHYROIDISM (Graves' disease), not hypothyroidism.
  • D. Polyuria, polydipsia, and fatigue are classic signs of diabetes mellitus — not hypothyroidism.

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