Pathology · single question

For mucositis after radiation or chemotherapy, what rinse is commonly prescribed?

  1. Nystatin oral suspension
  2. Triamcinolone in Orabase
  3. Magic mouthwash (antacid + steroid + antifungal + anesthetic + antibiotic combinations)
  4. Chlorhexidine alone
Show answer and explanation

Correct answer: C. Magic mouthwash (antacid + steroid + antifungal + anesthetic + antibiotic combinations)

  • A. Nystatin is specifically antifungal — used for oral candidiasis, not mucositis.
  • B. Triamcinolone is used for aphthous ulcers — not typically mucositis cocktails.
  • C. Correct. 'Magic mouthwash' for mucositis post-radiation/chemo typically combines several agents: an antacid (Maalox/Mylanta) to coat the mucosa, a corticosteroid to reduce inflammation, an antifungal (nystatin) for fungal superinfection, a local anesthetic (lidocaine/diphenhydramine) for pain relief, and sometimes an antibiotic. Formulas vary by institution. Chlorhexidine may also be used as an adjunct. Note: magic mouthwash does NOT typically contain antivirals.
  • D. Chlorhexidine alone is insufficient for mucositis management.

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