Prosthodontics & Occlusion · single question
For MANAGEMENT OF MRONJ (medication-related osteonecrosis of the jaw) from bisphosphonates, what is the BEST approach?
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Correct answer: D. Conservative management — debridement of necrotic tissue, antimicrobial rinses, antibiotics; refer to oral/maxillofacial surgeon; avoid aggressive surgery
- A. Immediate surgical resection is reserved for advanced cases and can worsen the condition if done aggressively.
- B. Extracting adjacent teeth is generally avoided as it creates new extraction sites at risk for MRONJ.
- C. Hyperbaric oxygen is used for osteoradionecrosis (radiation-induced), not typically first-line for MRONJ.
- D. Correct. MRONJ management depends on the stage. The current approach favors CONSERVATIVE management: (1) gentle debridement of sequestrum, (2) CHX rinses, (3) systemic antibiotics (penicillin, metronidazole), (4) pain management, (5) referral to oral/maxillofacial surgeon for specialized management. Aggressive surgical resection can worsen MRONJ by exposing more bone. Stage III (severe cases with pathologic fractures) may require surgical intervention.
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