For a biopsy in the retromolar pad area, which nerves should be anesthetized?

The retromolar pad region receives innervation from multiple branches of the trigeminal nerve. The inferior alveolar nerve (via the mandibular nerve block) provides sensation to the mandibular posterior teeth and adjacent structures. The long buccal nerve (a branch of the mandibular nerve that runs buccal to the retromolar pad) innervates the buccal gingiva and mucosa posterior to the mental foramen. Both nerves must be anesthetized for complete coverage of the retromolar pad. The lingual nerve may also be blocked for lingual soft tissue coverage, though the primary nerves are the inferior alveolar and long buccal.