Factor V Leiden is a genetic condition that predisposes to:

Factor V Leiden makes factor V resistant to inactivation by activated protein C, producing a hypercoagulable state with increased risk of venous thromboembolism.Other options: It causes clotting, not bleeding; it is not primarily an anemia or immune disorder.Key exam takeaway: Factor V Leiden = hypercoagulable (thrombophilia), increased venous thrombosis risk.