Medical Emergencies · single question

Diabetic Ketoacidosis (DKA) is characterized by all of the following EXCEPT:

  1. Metabolic acidosis (pH <7.3)
  2. Ketosis (elevated ketone bodies)
  3. Hyperglycemia (elevated blood glucose)
  4. Decreased gluconeogenesis
Show answer and explanation

Correct answer: D. Decreased gluconeogenesis

DKA is characterized by INCREASED gluconeogenesis (not decreased). In DKA, insulin deficiency leads to: (1) unopposed glucagon action → increased gluconeogenesis and glycogenolysis → hyperglycemia; (2) increased lipolysis → free fatty acids → ketogenesis → ketosis; (3) accumulation of ketone bodies (acetoacetate, beta-hydroxybutyrate) → metabolic acidosis. Gluconeogenesis is ELEVATED in DKA, not decreased. Decreased gluconeogenesis is the EXCEPTION.

Practice Medical Emergencies questions Medical Emergencies study notes

More Medical Emergencies practice questions