Medical Emergencies · single question
Diabetic Ketoacidosis (DKA) is characterized by all of the following EXCEPT:
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Correct answer: D. Decreased gluconeogenesis
DKA is characterized by INCREASED gluconeogenesis (not decreased). In DKA, insulin deficiency leads to: (1) unopposed glucagon action → increased gluconeogenesis and glycogenolysis → hyperglycemia; (2) increased lipolysis → free fatty acids → ketogenesis → ketosis; (3) accumulation of ketone bodies (acetoacetate, beta-hydroxybutyrate) → metabolic acidosis. Gluconeogenesis is ELEVATED in DKA, not decreased. Decreased gluconeogenesis is the EXCEPTION.
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