Pathology · single question

Continuing denture stomatitis case: appropriate treatment for the candidal infection?

  1. Chlorhexidine rinse alone
  2. Systemic amoxicillin
  3. Doxycycline
  4. Nystatin (topical antifungal)
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Correct answer: D. Nystatin (topical antifungal)

NYSTATIN (polyene antifungal): first-line for oral candidiasis associated with denture stomatitis. Binds ergosterol in fungal cell membrane → pores → cell lysis. For resistant/severe cases: systemic fluconazole. Must combine with denture hygiene and nighttime removal.

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