Anatomy & Histology · single question

Collagen fibers first begin to form during wound healing at approximately which time point?

  1. 5 days
  2. 2 weeks
  3. 2 days
  4. 4 weeks
Show answer and explanation

Correct answer: C. 2 days

  • A. ❌ By day 5, collagen fibers are abundant and bridging the wound, but this is not the initial formation time.
  • B. ❌ At 2 weeks, continued collagen accumulation occurs during the proliferative/early remodeling phase.
  • C. Collagen fiber formation begins early in the proliferative phase. Source answer: 2 days. ⚠️ See flag — established textbooks cite day 3–5 for active collagen deposition.
  • D. ❌ At 4 weeks, remodeling is underway — not the start of collagen formation.

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