Pathology · single question

Civatte bodies (colloid/apoptotic keratinocytes) are characteristically seen in:

  1. Lichen planus
  2. Pemphigus vulgaris
  3. Lupus erythematosus
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Correct answer: A. Lichen planus

  • A. Correct. Civatte (colloid) bodies — apoptotic basal keratinocytes — are a histologic feature of lichen planus, along with band-like lymphocytic infiltrate and basal cell degeneration.
  • B. Incorrect. Pemphigus shows intraepithelial acantholysis and Tzanck cells, not Civatte bodies.
  • C. Incorrect. Lupus shows basement-membrane changes and a deeper perivascular infiltrate; Civatte bodies are the lichen planus marker.

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