Biostatistics & Research · single question

Bias that specifically arises from the systematic way participants are both CHOSEN and LOST from a study is best called:

  1. Reporting bias
  2. Sampling bias
  3. Selection bias
  4. Attrition bias
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Correct answer: D. Attrition bias

Attrition bias (follow-up bias) occurs when participants drop out in a non-random manner, affecting who completes the study and thus the validity of results.
  • A. Reporting bias refers to selective reporting of outcomes/results, not participant selection or retention.
  • B. Sampling bias refers to errors in how the sample was chosen from the population — not specifically about loss of participants during the study.
  • C. Selection bias refers to systematic errors in who is recruited at baseline, not who is retained.
  • D. CORRECT. Attrition bias = systematic differences between those who complete the study and those who drop out. When combined with how participants were initially selected, this compromises both internal and external validity.

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