Apixaban exerts its anticoagulant effect by inhibiting which clotting factor?

Apixaban (like rivaroxaban) is a direct factor Xa inhibitor; reversal agents include andexanet alfa and prothrombin complex concentrates.Other options: Direct thrombin (IIa) inhibition describes dabigatran; vitamin K epoxide reductase inhibition describes warfarin.Key exam takeaway: Apixaban/rivaroxaban = direct factor Xa inhibitors; dabigatran = direct thrombin inhibitor.