Pharmacology · single question
Antiplaque and anti-gingivitis properties in toothpaste are BEST attributed to which fluoride compound?
Show answer and explanation
Correct answer: D. Stannous fluoride (SnF2)
- A. Sodium fluoride (NaF) is effective for caries prevention but does not have the same antiplaque/anti-gingivitis evidence as stannous fluoride.
- B. APF is used professionally for caries prevention; it is not a toothpaste ingredient with anti-gingivitis indications.
- C. Sodium monofluorophosphate (MFP) is a common anti-caries fluoride but lacks the antimicrobial/anti-gingivitis properties of stannous fluoride.
- D. Correct. Stannous fluoride (SnF2) has both anticaries properties and demonstrated antiplaque/anti-gingivitis activity due to the stannous (tin) ion's antibacterial effect on periodontal pathogens, reducing gingival inflammation.