Micro & Immunology · single question

Anaphylaxis is which type of hypersensitivity reaction (and what is its timing)?

  1. Type I — immediate
  2. Type II — delayed
  3. Type III — immune complex
  4. Type IV — delayed/cell-mediated
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Correct answer: A. Type I — immediate

  • A. Correct. Anaphylaxis is a type I, IgE-mediated, IMMEDIATE hypersensitivity reaction (mast cell/basophil degranulation within minutes). Treat with intramuscular epinephrine.
  • B. Type II is cytotoxic, not the basis of anaphylaxis.
  • C. Type III is immune-complex mediated.
  • D. Type IV is delayed and T-cell mediated.

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