Anatomy & Histology · single question

All of the following tissues are derived from mesenchymal cells EXCEPT:

  1. Buccal mucosa (oral epithelium)
  2. Bone
  3. Cartilage
  4. Skeletal muscles
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Correct answer: A. Buccal mucosa (oral epithelium)

The buccal mucosa is lined by stratified squamous epithelium, which is derived from ectoderm (surface epithelium of the stomodeum/oral ectoderm), NOT from mesenchymal cells. Mesenchymal cells (derived from mesoderm and neural crest cells) give rise to: bone, cartilage, adipose tissue, connective tissue, smooth muscle, and skeletal muscle. In the head and neck, most craniofacial mesenchyme is neural crest-derived. The oral epithelium (buccal mucosa, gingival epithelium, taste buds) is ectodermal in origin. This is a key histological distinction tested in dental board examinations.

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